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Contraindicated (1)pentobarbital will reduce the extent or effect of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers can lead to decreased serum concentrations and lack of antimalarial efficacypentobarbital will lower the level or effect of eltrombopag by impacti